Outcomes of primary total joint arthroplasty after lung transplantation

J Arthroplasty. 2014 Jan;29(1):11-5. doi: 10.1016/j.arth.2013.03.029. Epub 2013 Apr 30.

Abstract

Lung transplantation is increasingly common with improving survival rates. Post-transplant patients can be expected to seek total hip (THA) and knee arthroplasty (TKA) to improve their quality of life. Outcomes of 20 primary total joint arthroplasties (15 THA, 5 TKA) in 14 patients with lung transplantation were reviewed. Clinical follow-up time averaged 27.5 and 42.8 months for THA and TKA respectively. Arthroplasty indications included osteonecrosis, osteoarthritis, and fracture. All patients subjectively reported good or excellent outcomes with a final average Harris Hip Score of 88.7, Knee Society objective and functional score of 92.0. There were 4 minor and 1 major acute perioperative complications. 1 late TKA infection was successfully treated with two-stage revision. The mortality rate was 28.5% (4/14 patients) at an average 20.6 months following but unrelated to arthroplasty. Overall, total joint arthroplasty can be safely performed and provide good functional outcomes in lung transplant recipients.

Keywords: hip arthroplasty; immunosuppression; knee arthroplasty; lung transplantation.

MeSH terms

  • Aged
  • Arthroplasty, Replacement, Hip*
  • Arthroplasty, Replacement, Knee*
  • Female
  • Fractures, Bone / surgery
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Joint Diseases / complications
  • Joint Diseases / etiology
  • Joint Diseases / surgery*
  • Lung Diseases / complications
  • Lung Diseases / drug therapy
  • Lung Diseases / surgery*
  • Lung Transplantation*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Immunosuppressive Agents