Zoster paresis: asymptomatic MRI lesions far beyond the site of rash and focal weakness

J Neurol Sci. 2013 Jul 15;330(1-2):119-20. doi: 10.1016/j.jns.2013.04.009. Epub 2013 Apr 28.

Abstract

We describe a patient with zoster paresis and an MRI that revealed extensive spinal cord lesions from the upper cervical to the lower thoracic spinal cord. Importantly, the patient reported considerable spontaneous improvement in strength 2-3 weeks after zoster. This report reveals a previously undescribed remarkable preponderance of MRI lesions far beyond the site of zoster rash and focal lower motor neuron weakness.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Acyclovir / adverse effects
  • Acyclovir / analogs & derivatives
  • Acyclovir / therapeutic use
  • Aged
  • Antiviral Agents / adverse effects
  • Antiviral Agents / therapeutic use
  • Exanthema / pathology*
  • Female
  • Herpes Zoster / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Motor Neuron Disease / pathology
  • Muscle Weakness / pathology*
  • Spinal Cord / pathology
  • Spinal Nerve Roots / pathology
  • Valacyclovir
  • Valine / adverse effects
  • Valine / analogs & derivatives
  • Valine / therapeutic use

Substances

  • Antiviral Agents
  • Valine
  • Valacyclovir
  • Acyclovir