Solitary fibrous tumours of the pleura: report of two cases and literature review

Ir J Med Sci. 2013 Dec;182(4):729-33. doi: 10.1007/s11845-013-0952-8. Epub 2013 Apr 23.

Abstract

Background: Solitary fibrous tumours of the pleura (SFTPs) are rare pleural mesenchymal neoplasms with distinct clinicopathological and immunohistochemical features, accounting for less than 5 % of all neoplasms involving the pleura.

Methods: We present two cases of SFTP with a review of the current literature.

Results: Clinical presentation varies according to size and intrathoracic localisation. The molecular pathology of SFTPs is largely unknown. Complete surgical resection is recommended with long-term clinic and radiographic follow-up due to its malignant potential.

Conclusions: This is a summary of available literature outlining current clinical practice in the diagnosis, management, and treatment of SFTPs in Ireland.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Biopsy
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Pneumonectomy
  • Solitary Fibrous Tumor, Pleural* / diagnostic imaging
  • Solitary Fibrous Tumor, Pleural* / pathology
  • Solitary Fibrous Tumor, Pleural* / surgery
  • Thoracotomy
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Tumor Burden

Substances

  • Biomarkers, Tumor