Radionuclide impurities in [¹⁸F]F⁻ and [¹⁸F]FDG for positron emission tomography

M Köhler; D Degering; J Zessin; F Füchtner; J Konheiser

doi:10.1016/j.apradiso.2013.03.044

Radionuclide impurities in [¹⁸F]F⁻ and [¹⁸F]FDG for positron emission tomography

Appl Radiat Isot. 2013 Nov:81:268-71. doi: 10.1016/j.apradiso.2013.03.044. Epub 2013 Mar 22.

Authors

M Köhler¹, D Degering, J Zessin, F Füchtner, J Konheiser

Affiliation

¹ Verein für Kernverfahrenstechnik und Analytik Rossendorf e.V. (VKTA), P.O. Box 510119, D-01314 Dresden, Germany. matthias.koehler@vkta.de

PMID: 23608142
DOI: 10.1016/j.apradiso.2013.03.044

Abstract

The paper describes radionuclide impurities (γ-emitters and (3)H) in proton irradiated (18)O enriched water from an Nb target vessel with Nb entrance window, their distribution in different synthesis steps and finally in the PET radiopharmaceuticals [(18)F]Fluoride and [(18)F]FDG.

Keywords: (18)F; PET; Radionuclidic purity.

MeSH terms

Contrast Media / analysis*
Drug Contamination / prevention & control*
Fluorodeoxyglucose F18 / analysis
Fluorodeoxyglucose F18 / chemistry*
Gamma Rays
Germany
Materials Testing
Positron-Emission Tomography*
Radiation Dosage
Radiometry / methods*
Radiopharmaceuticals / analysis
Radiopharmaceuticals / chemistry
Tritium / analysis*

Substances

Contrast Media
Radiopharmaceuticals
Fluorodeoxyglucose F18
Tritium