Comparison of profile of retinopathy of prematurity in semiurban/rural and urban NICUs in Karnataka, India

Br J Ophthalmol. 2013 Jun;97(6):687-9. doi: 10.1136/bjophthalmol-2012-302801. Epub 2013 Apr 19.

Abstract

Purpose: To identify and compare the profile of retinopathy of prematurity (ROP) in premature babies in urban and semiurban neonatal intensive care units (NICUs).

Methods: A prospective study of babies admitted to NICUs of two urban and seven semiurban centres. They were <36 weeks of gestational age and were subjected to fundus photography with a RetCam shuttle camera. Photos and NICU details were uploaded on a secure website. Photographs were read by a single observer. Infants were followed till retinal vascularisation was complete, or 45 weeks post conceptional age. Babies developing severe ROP were lasered.

Results: 500 babies were screened (243, urban group; 257, semiurban group). Incidence of ROP in the urban and semiurban groups was 16.5% (40) and 14.8% (38) respectively. Mean gestational age was 30.90 weeks and 31.53 weeks respectively. Mean birth weight was 1344 g and 1375 g respectively. 28 babies were lasered, 15 and 13 from each group respectively. There was no statistically significant difference between any of the parameters compared. Level of significance was fixed at 0.05.

Conclusions: The magnitude of the burden of ROP is comparable between urban and semiurban NICUs stressing the need for effective screening strategies in semiurban and rural areas as well.

Keywords: Epidemiology; Retina; Telemedicine.

Publication types

  • Comparative Study

MeSH terms

  • Birth Weight
  • Female
  • Humans
  • Incidence
  • India / epidemiology
  • Infant, Newborn
  • Infant, Premature*
  • Intensive Care Units, Neonatal / statistics & numerical data*
  • Intensive Care, Neonatal*
  • Male
  • Prospective Studies
  • Retinopathy of Prematurity / diagnosis*
  • Retinopathy of Prematurity / epidemiology*
  • Rural Population / statistics & numerical data
  • Urban Population / statistics & numerical data