Acrophialophora fusispora brain abscess in a patient with acquired immunodeficiency syndrome: a case report and review of the literature

Diagn Microbiol Infect Dis. 2013 Jul;76(3):368-71. doi: 10.1016/j.diagmicrobio.2013.03.016. Epub 2013 Apr 17.

Abstract

We reported a fatal case of brain abscess caused by Acrophialophora fusispora in a patient with acquired immunodeficiency syndrome. Identification of the fungus was based on microscopic morphology and sequence analyses of the internal transcribed spacer 1 (ITS1) and 2 (ITS2) of ribosomal RNA gene from the isolate recovered from brain abscess. Four published cases were reviewed as well.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Ascomycota / genetics
  • Ascomycota / isolation & purification*
  • Brain Abscess / diagnosis*
  • Brain Abscess / drug therapy
  • Brain Abscess / microbiology
  • Central Nervous System Fungal Infections / diagnosis*
  • Central Nervous System Fungal Infections / drug therapy
  • Central Nervous System Fungal Infections / microbiology
  • Fatal Outcome
  • Humans
  • Male
  • Middle Aged
  • Multilocus Sequence Typing
  • Mycological Typing Techniques