Consensus guidelines for the management and treatment of neuroendocrine tumors

Pancreas. 2013 May;42(4):557-77. doi: 10.1097/MPA.0b013e31828e34a4.

Abstract

Neuroendocrine tumors are a heterogeneous group of tumors originating in various anatomic locations. The management of this disease poses a significant challenge because of the heterogeneous clinical presentations and varying degrees of aggressiveness. The recent completion of several phase 3 trials, including those evaluating octreotide, sunitinib, and everolimus, demonstrate that rigorous evaluation of novel agents in this disease is possible and can lead to practice-changing outcomes. Nevertheless, there are many aspects to the treatment of neuroendocrine tumors that remain unclear and controversial. The North American Neuroendocrine Tumor Society published a set of consensus guidelines in 2010, which provided an overview for the treatment of patients with these malignancies. Here, we present a set of consensus tables intended to complement these guidelines and serve as a quick, accessible reference for the practicing physician.

Publication types

  • Consensus Development Conference
  • Practice Guideline

MeSH terms

  • Biomarkers, Tumor / metabolism
  • Humans
  • Molecular Targeted Therapy
  • Neuroendocrine Tumors / metabolism
  • Neuroendocrine Tumors / pathology
  • Neuroendocrine Tumors / therapy*
  • North America
  • Societies, Medical

Substances

  • Biomarkers, Tumor