Surgery for pulmonary malignancies in patients with a previous history of head and neck squamous cell carcinoma

Surg Today. 2014 Apr;44(4):646-52. doi: 10.1007/s00595-013-0593-6. Epub 2013 Apr 16.

Abstract

Purpose: To examine the perioperative and long-term outcomes of surgery for malignancies of the lungs in patients with a history of head and neck squamous cell carcinoma (HNSCC) and to evaluate the risk factors associated with postoperative complications.

Methods: The data of 39 patients with a history of HNSCC who underwent pulmonary resection were reviewed. The perioperative and long-term outcomes were analyzed.

Results: Eight patients (21%) had difficult airways, and nine patients (23%) developed postoperative complications. A low body mass index (<18.5), a history of malignancy besides HNSCC and chronic obstructive pulmonary disease were each found to be significantly associated with the development of postoperative complications. The 5-year survival rate of all patients was 80%.

Conclusions: The airway management of patients with a history of HNSCC should be carefully undertaken. Preoperative assessment of their nutritional status and careful prevention of air leakage during surgery are important. Because favorable outcomes can be achieved, aggressive surgical management should be considered for the treatment of pulmonary malignancies in patients with a history of HNSCC.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Airway Management
  • Anastomotic Leak / prevention & control
  • Carcinoma, Squamous Cell / mortality
  • Carcinoma, Squamous Cell / secondary*
  • Carcinoma, Squamous Cell / surgery*
  • Female
  • Head and Neck Neoplasms / pathology*
  • Humans
  • Lung Neoplasms / mortality
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery*
  • Male
  • Middle Aged
  • Nutritional Status
  • Perioperative Care
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Pulmonary Disease, Chronic Obstructive
  • Risk Factors
  • Survival Rate
  • Treatment Outcome
  • Young Adult