Additive potential of ginger starch on antifungal potency of honey against Candida albicans

Asian Pac J Trop Biomed. 2012 Apr;2(4):253-5. doi: 10.1016/S2221-1691(12)60018-5.

Abstract

Objective: To evaluate the additive action of ginger starch on the antifungal activity of honey against Candida albicans (C. albicans).

Methods: C. albicans was used to determine the minimum inhibitory concentration (MIC) of four varieties of Algerian honey. Lower concentrations of honey than the MIC were incubated with a set of concentrations of starch and then added to media to determine the minimum additive inhibitory concentration (MAIC).

Results: The MIC for the four varieties of honey without starch against C. albicans ranged between 38% and 42% (v/v). When starch was incubated with honey and then added to media, a MIC drop was noticed with each variety. MAIC of the four varieties ranged between 32% honey (v/v) with 4% starch and 36% honey (v/v) with 2% starch.

Conclusions: The use of ginger starch allows honey benefit and will constitute an alternative way against the resistance to antifungal agents.

Keywords: Antifungal potency; Candida albicans; Ginger starch; Honey.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / pharmacology*
  • Candida albicans / drug effects*
  • Honey*
  • Microbial Sensitivity Tests
  • Plant Extracts / pharmacology*
  • Zingiber officinale / chemistry*

Substances

  • Antifungal Agents
  • Plant Extracts