Pharmacological screening of methanolic extract of Ixora species

Asian Pac J Trop Biomed. 2012 Feb;2(2):149-51. doi: 10.1016/S2221-1691(11)60210-4.

Abstract

Objective: To investigate the antimicrobial activity of methanolic extracts of different parts of Ixora species.

Methods: Antimicrobial activity was carried out using disc diffusion assay against fungi, gram-positive and gram-negative bacteria.

Results: All methanolic extracts of different parts of Ixora species showed a broad-spectrum of antibacterial and antiyeast activities, which inhibited the growth of at least one bacterium or yeast. There was no remarkable difference between different Ixora species observed in this study.

Conclusions: The significant antimicrobial activity shown by this Ixora species suggests its potential against infections caused by pathogens. The extract may be developed as an antimicrobial agent.

Keywords: Antibacterial; Antimicrobial activity; Antiyeast; Infectious agent; Ixora species.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Antifungal Agents / pharmacology
  • Fungi / drug effects*
  • Gram-Negative Bacteria / drug effects*
  • Gram-Positive Bacteria / drug effects*
  • Microbial Sensitivity Tests
  • Phytotherapy
  • Plant Extracts / pharmacology*
  • Rubiaceae / classification
  • Rubiaceae / metabolism*

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Plant Extracts