Advances in esophageal surgery in elderly patients with thoracic esophageal cancer

Anticancer Res. 2013 Apr;33(4):1641-7.

Abstract

Aim: To justify esophagectomy for elderly patients.

Patients and methods: A total of 1,002 patients with thoracic esophageal cancer who underwent esophagectomy were divided into three groups: I (≤ 74 years old, n=898); II (75-79 years, n=81); and III (≥ 80 years, n=23). Historical changes were compared between the first surgical period (1964-1989) and the second period (1990-2011).

Results: The morbidity rates were 40%, 41% and 26% in the respective groups. Pulmonary complications decreased historically in groups II and III (36% to 15% and 43% to 0%, respectively). The mortality was higher in the older groups (4.8%, 8.6% and 13.0%, respectively); however, there was a marked historical decrease in groups II (18.2% to 5.1%) and III (28.6% to 6.3%). The 5-year survival improved from 5% to 35% in group II and from 0% to 17% in group III.

Conclusion: The outcomes of esophagectomy for elderly patients have markedly improved, with acceptable mortality even in octogenarians.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / mortality
  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery*
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / mortality
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery*
  • Esophageal Neoplasms / mortality
  • Esophageal Neoplasms / pathology
  • Esophageal Neoplasms / surgery*
  • Esophagectomy / mortality*
  • Female
  • Humans
  • Lung Diseases / etiology*
  • Male
  • Middle Aged
  • Postoperative Complications*
  • Prognosis
  • Risk Factors
  • Survival Rate
  • Thoracic Neoplasms / mortality
  • Thoracic Neoplasms / pathology
  • Thoracic Neoplasms / surgery*
  • Tomography, X-Ray Computed