Abstract
Magnetic ionic liquids (MILs) are new solvents with an interesting broad of applications however their toxicity is still an open issue. In this paper we report the toxicity of [C(8)MIM] and [Choline-C(n)] based magnetic ionic liquids assessed in two human cell lines: normal skin fibroblasts (CRL-1502) and colorectal adenocarcinoma cells (CaCo-2), acquiring this last characteristics of human enterocytes after differentiation. The results showed that [CoCl(4)] and [MnCl(4)] are more prone to generate cytotoxicity.
Copyright © 2013 Elsevier Ltd. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Caco-2 Cells
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Cell Line
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Cell Survival / drug effects
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Chlorides / chemistry
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Chlorides / toxicity
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Cobalt / chemistry
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Cobalt / toxicity
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Environmental Pollutants / chemistry
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Environmental Pollutants / toxicity*
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Humans
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Ionic Liquids / chemical synthesis
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Ionic Liquids / chemistry
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Ionic Liquids / toxicity*
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Magnetics*
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Manganese Compounds / chemistry
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Models, Chemical
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Solvents / chemistry
Substances
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Chlorides
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Environmental Pollutants
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Ionic Liquids
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Manganese Compounds
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Solvents
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Cobalt
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cobaltous chloride
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manganese chloride