Genetic diversity and antibiotic resistance in Escherichia coli from environmental surface water in Dhaka City, Bangladesh

M Kamruzzaman; Shereen Shoma; S M Naymul Bari; Andrew N Ginn; Agnieszka M Wiklendt; Sally R Partridge; Shah M Faruque; Jonathan R Iredell

doi:10.1016/j.diagmicrobio.2013.02.016

Genetic diversity and antibiotic resistance in Escherichia coli from environmental surface water in Dhaka City, Bangladesh

Diagn Microbiol Infect Dis. 2013 Jun;76(2):222-6. doi: 10.1016/j.diagmicrobio.2013.02.016. Epub 2013 Mar 28.

Authors

M Kamruzzaman¹, Shereen Shoma, S M Naymul Bari, Andrew N Ginn, Agnieszka M Wiklendt, Sally R Partridge, Shah M Faruque, Jonathan R Iredell

Affiliation

¹ Centre for Research Excellence in Critical Infection and Sydney Institute for Emerging Infections and Biosecurity, University of Sydney, Sydney, New South Wales, Australia.

PMID: 23541688
DOI: 10.1016/j.diagmicrobio.2013.02.016

Abstract

The extended-spectrum β-lactamase gene bla(CTX-M-15) was almost ubiquitous in diverse antibiotic-resistant Escherichia coli isolated from surface water around Dhaka City, Bangladesh. Forty-eight isolates represented 34 multi-locus sequence types and a variety of plasmid replicons were identified in association with bla(CTX-M-15) and other resistance genes. This water is likely to be an important source of transmissible antibiotic resistance in Bangladesh.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology
Bangladesh
DNA, Bacterial / genetics
Drug Resistance, Multiple, Bacterial*
Escherichia coli / drug effects*
Escherichia coli / genetics*
Escherichia coli / isolation & purification
Genetic Loci
Genetic Variation*
Microbial Sensitivity Tests
Plasmids / drug effects
Water Microbiology*
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
DNA, Bacterial
beta-Lactamases