Abstract
This communication describes an ultrafast high-sensitivity plasmonic-driven thermal sensing approach for the detection of tumoral markers. Gold nanoprisms derivatized with antibody against carcinoembryonic antigen (anti-CEA) are used to label CEA molecules and imprint thermal signals upon illumination, enabling sensitivities up to the attomolar range in real patient samples.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibodies / chemistry*
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Biomarkers, Tumor / blood*
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Biomarkers, Tumor / immunology
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Biosensing Techniques*
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Carcinoembryonic Antigen / blood*
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Carcinoembryonic Antigen / immunology
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Gold / chemistry*
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Hot Temperature
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Humans
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Nanostructures / chemistry*
Substances
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Antibodies
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Biomarkers, Tumor
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Carcinoembryonic Antigen
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Gold