Abstract
Three human rotavirus G9P[8] strains, RVA/Human-tc/KOR/CAU05-202/2005/G9P[8], RVA/Human-tc/KOR/CAU09-371/2009/G9P[8], and RVA/Human-tc/KOR/CAU09-376/2009/G9P[8], were isolated from female pediatric patients with diarrhea from 2005 to 2009 using a cell culture system, and their complete genomic sequences were analyzed. The 11 gene segments of the three Korean strains possessed the G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1 genotype, which is closely related to the Wa-like genotype 1 constellation. Interestingly, the NSP2 and the NSP3 genes of strain RVA/Human-tc/KOR/CAU09-376/2009/G9P[8] were related to the G9 porcine or human-porcine reassortant strains, providing evidence for porcine-to-human interspecies transmission.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Child, Preschool
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Cluster Analysis
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Diarrhea / virology
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Evolution, Molecular
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Female
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Genome, Viral*
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Humans
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Infant
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Molecular Sequence Data
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Phylogeny
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RNA, Viral / genetics*
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Republic of Korea
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Rotavirus / classification*
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Rotavirus / genetics*
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Rotavirus / isolation & purification
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Rotavirus Infections / virology*
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Sequence Analysis, DNA*
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Sequence Homology
Associated data
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GENBANK/JF766573
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GENBANK/JF766574
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GENBANK/JF766575
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GENBANK/JF766576
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GENBANK/JF766577
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GENBANK/JF766578
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GENBANK/JF766600
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GENBANK/JF766601
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GENBANK/JF766602