Abstract
We report a reagentless and reusable "signal-on" electrochemical DNA sensor that utilizes oligo-thymine as a flexible spacer. This sensor design is sensitive, specific, and selective; it is potentially generalizable for detection of a wide range of biomedical-relevant nucleic acid sequences.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Biosensing Techniques
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DNA / analysis*
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DNA / genetics
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DNA / metabolism
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DNA Probes / chemistry
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DNA Probes / metabolism
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Electrochemical Techniques*
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Electrodes
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Gold / chemistry
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Methylene Blue / metabolism
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Nucleic Acid Hybridization
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Oligonucleotides / chemistry*
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Point Mutation
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Thymine / chemistry*
Substances
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DNA Probes
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Oligonucleotides
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Gold
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DNA
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Thymine
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Methylene Blue