Hyperthyroidism and pregnancy

Endocrinol Nutr. 2013 Nov;60(9):535-43. doi: 10.1016/j.endonu.2012.11.006. Epub 2013 Mar 7.
[Article in English, Spanish]

Abstract

Association of hyperthyroidism and pregnancy is not an unusual event, and has an impact on both the mother and fetus. After delivery, it may also affect the newborn and the nursing mother. Clinical management of this situation is quite different from that required by non-pregnant hyperthyroid women and poses significant diagnostic and therapeutic challenges. This review addresses aspects related to the unique characteristics of biochemical assessment of thyroid function in pregnancy, the potential causes of hyperthyroidism in pregnancy, and the clinical and therapeutic approach in each case. Special attention is paid to pregnancy complicated with Graves' disease and its different the maternal, fetal, neonatal, and postnatal consequences.

Keywords: Embarazo; Enfermedad de Graves; Gestational transient thyrotoxicosis; Graves’ disease; Hiperemesis gravídica; Hipertiroidismo; Hyperemesis gravidarum; Hyperthyroidism; Pregnancy; Tirotoxicosis gestacional transitoria.

Publication types

  • Review

MeSH terms

  • Female
  • Fetal Diseases / diagnosis
  • Graves Disease / diagnosis
  • Humans
  • Hyperthyroidism* / diagnosis
  • Pregnancy
  • Pregnancy Complications* / diagnosis