Methyl 12-hydroxy-10-[1-(4-meth-oxy-phen-yl)-2-oxo-3-phen-oxy-azetidin-4-yl]-11-oxa-3-aza-hexa-cyclo-[11.7.1.0(2,9).0(2,12).0(3,7).0(17,21)]henicosa-1(20),13,15,17(21),18-penta-ene-9-carboxyl-ate

Sivasubramanian Suhitha; Thothadri Srinivasan; Raju Rajesh; Raghavachary Raghunathan; Devadasan Velmurugan

doi:10.1107/S1600536812045795

Methyl 12-hydroxy-10-[1-(4-meth-oxy-phen-yl)-2-oxo-3-phen-oxy-azetidin-4-yl]-11-oxa-3-aza-hexa-cyclo-[11.7.1.0(2,9).0(2,12).0(3,7).0(17,21)]henicosa-1(20),13,15,17(21),18-penta-ene-9-carboxyl-ate

Acta Crystallogr Sect E Struct Rep Online. 2012 Dec 1;68(Pt 12):o3329-30. doi: 10.1107/S1600536812045795. Epub 2012 Nov 10.

Authors

Sivasubramanian Suhitha¹, Thothadri Srinivasan, Raju Rajesh, Raghavachary Raghunathan, Devadasan Velmurugan

Affiliation

¹ Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India.

Abstract

In the title compound, C37H34N2O7, both pyrrolidine rings adopt envelope conformations. The β-lactam ring is close to planar (r.m.s. deviation = 0.0395 Å) and makes a dihedral angle of 83.35 (15)° with the furan ring. The O atom attached to the β-lactam ring deviates by 0.187 (2) Å from the mean plane of the ring. The β-lactam ring makes dihedral angles of 14.90 (15) and 27.72 (17)° with the meth-oxy-phenyl and phenyl rings, respectively. The crystal packing features C-H⋯O hydrogen bonds.