Norcucurbitane triterpenoids from the fruits of Momordica charantia var. abbreviata

Yun-Wen Liao; Chiy-Rong Chen; Jue-Liang Hsu; Yun-Sheng Lin; Hsueh-Ling Cheng; Wen-Ling Shih; Yueh-Hsiung Kuo; Chi-I Chang

Norcucurbitane triterpenoids from the fruits of Momordica charantia var. abbreviata

Nat Prod Commun. 2013 Jan;8(1):79-81.

Authors

Yun-Wen Liao¹, Chiy-Rong Chen, Jue-Liang Hsu, Yun-Sheng Lin, Hsueh-Ling Cheng, Wen-Ling Shih, Yueh-Hsiung Kuo, Chi-I Chang

Affiliation

¹ Department of Biological Science and Technology, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan.

PMID: 23472465

Abstract

Two new 27-norcucurbitane triterpenoids, 27-nor-3beta-hydroxy-7beta-methoxycucurbita-5,23(E)-dien-25-one (1) and 27-nor-3beta-hydroxy-5beta,19-epoxycucurbita-6,23(E)-dien-25-one (2), together with two known cucurbitane triterpenes, 23(E)-7beta-methoxycucurbita-5,23,25-trien-3beta-ol (3) and 5beta,19-epoxy-25-methoxycucurbita-6,23(E)-dien-3beta-ol (4), were isolated from the fruits of Momordica charantia var. abbreviata. Their structures were determined by analysis of spectroscopic data and comparison with the data of known analogues.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fruit / chemistry
Molecular Structure
Momordica charantia / chemistry*
Triterpenes / chemistry
Triterpenes / isolation & purification*

Substances

27-nor-3beta-hydroxy-5beta,19-epoxycucurbita-6,23(E)-dien-25-one
27-nor-3beta-hydroxy-7beta-methoxycucurbita-5,23(E)-dien-25-one
Triterpenes