Combination of rituximab with therapeutic plasma exchange in a refractory case of thrombotic thrombocytopenic purpura (TTP)

Rekha Hans; Ratti Ram Sharma; Neelam Marwaha

doi:10.1016/j.transci.2012.09.007

Combination of rituximab with therapeutic plasma exchange in a refractory case of thrombotic thrombocytopenic purpura (TTP)

Transfus Apher Sci. 2013 Oct;49(2):231-3. doi: 10.1016/j.transci.2012.09.007. Epub 2013 Mar 5.

Authors

Rekha Hans¹, Ratti Ram Sharma, Neelam Marwaha

Affiliation

¹ Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Electronic address: drhansrekha@gmail.com.

PMID: 23466013
DOI: 10.1016/j.transci.2012.09.007

Abstract

Therapeutic plasma exchange is established treatment for patients with thrombotic thrombocytopenic purpura (TTP) and for refractory cases immunosuppressive therapy can also be considered. We present a refractory case of TTP which was managed with therapeutic plasma exchange and rituximab.

Keywords: Rituximab; Therapeutic plasma exchange; Thrombotic thrombocytopenic purpura (TTP).

Publication types

Case Reports

MeSH terms

Adult
Antibodies, Monoclonal, Murine-Derived / administration & dosage*
Antineoplastic Agents / administration & dosage*
Female
Humans
Plasma Exchange*
Purpura, Thrombotic Thrombocytopenic / therapy*
Rituximab

Substances

Antibodies, Monoclonal, Murine-Derived
Antineoplastic Agents
Rituximab