Isolation and characterization of new minor triterpenoid saponins from the buds of Lonicera macranthoides

Jiang Liu; Jing Zhang; Feng Wang; Yuan-feng Zou; Xing-fu Chen

doi:10.1016/j.carres.2013.01.019

Isolation and characterization of new minor triterpenoid saponins from the buds of Lonicera macranthoides

Carbohydr Res. 2013 Apr 5:370:76-81. doi: 10.1016/j.carres.2013.01.019. Epub 2013 Feb 4.

Authors

Jiang Liu¹, Jing Zhang, Feng Wang, Yuan-feng Zou, Xing-fu Chen

Affiliation

¹ Division of Pharmaceutical Botany, College of Agronomy, Sichuan Agricultural University, Chengdu 611130, PR China.

PMID: 23454139
DOI: 10.1016/j.carres.2013.01.019

Abstract

Three new minor compounds, 18-oleanene (1), lupine (2), and 12-oleanene (3) type triterpenoid saponins, along with four major known triterpenoid saponins were isolated from the buds of Lonicera macranthoides. Their structures were elucidated by spectroscopic and chemical analyses. 18-oleanene and lupine-type triterpenoid saponins were first isolated from this plant. The isolated compounds were evaluated for their cytotoxic activities against HSC-2 cells.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Lonicera / chemistry*
Plant Shoots / chemistry*
Saponins / chemistry*
Saponins / isolation & purification*
Triterpenes / chemistry*

Substances

Saponins
Triterpenes