A case of leukemia cutis presenting as histiocytoid Sweet's syndrome

Abstract

Background: Leukemia cutis (LC) represents a skin infiltration by leukemic cells. Clinically, it can mimic a wide variety of dermatoses.

Methods: We report a case of LC presenting with a Sweet's syndrome-like eruption and a histiocytoid Sweet's syndrome histologic manifestation.

Results: This case may represent distinct and important cutaneous and histopathologic manifestations of LC.

Conclusions: We believe that peripheral blood or bone marrow cytologic analysis is necessary in cases of LC to rule out the possibility of histiocytoid Sweet's syndrome. Additional study is needed to further elucidate the relationship between LC and histiocytoid Sweet's syndrome.