Early estimates of influenza vaccine effectiveness in Navarre, Spain: 2012/13 mid-season analysis

Euro Surveill. 2013 Feb 14;18(7):2.

Abstract

We present estimates of influenza vaccine effectiveness (VE) in Navarre, Spain, in the early 2012/13 season, which was dominated by influenza B. In a population-based cohort using electronic records from physicians, the adjusted VE in preventing influenzalike illness was 32% (95% confidence interval (CI): 15 to 46). In a nested test-negative case-control analysis the adjusted VE in preventing laboratory-confirmed influenza was 86% (95% CI: 45 to 96). These results suggest a high protective effect of the vaccine.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Hospitalization
  • Humans
  • Incidence
  • Influenza A Virus, H1N1 Subtype / immunology*
  • Influenza A Virus, H1N1 Subtype / isolation & purification
  • Influenza A Virus, H3N2 Subtype / immunology*
  • Influenza A Virus, H3N2 Subtype / isolation & purification
  • Influenza A Virus, H3N8 Subtype / immunology*
  • Influenza A Virus, H3N8 Subtype / isolation & purification
  • Influenza B virus / immunology*
  • Influenza B virus / isolation & purification
  • Influenza Vaccines / administration & dosage*
  • Influenza Vaccines / immunology
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control*
  • Influenza, Human / virology
  • Logistic Models
  • Male
  • Middle Aged
  • Population Surveillance
  • Prospective Studies
  • Seasons
  • Spain / epidemiology
  • Treatment Outcome
  • Vaccination / statistics & numerical data
  • Young Adult

Substances

  • Influenza Vaccines