Total synthesis of padanamides A and B

Chem Commun (Camb). 2013 Apr 14;49(29):2977-9. doi: 10.1039/c3cc00178d.

Abstract

The first total syntheses of padanamides A and B have been achieved, unambiguously confirming their structures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Cell Survival / drug effects
  • Cyclization
  • Humans
  • Jurkat Cells
  • Oligopeptides / chemical synthesis*
  • Oligopeptides / chemistry
  • Oligopeptides / toxicity
  • Palladium / chemistry
  • Stereoisomerism
  • Streptomyces / chemistry

Substances

  • Oligopeptides
  • padanamide A
  • padanamide B
  • Palladium