Clinical features associated with a rapid decline in renal function among Japanese patients with type 2 diabetes mellitus: microscopic hematuria coexisting with diabetic retinopathy

Misaki Sakata; Kentaro Oniki; Ayana Kita; Ayami Kajiwara; Yoshihiro Uchiyashiki; Junji Saruwatari; Akira Yoshida; Hideaki Jinnouchi; Kazuko Nakagawa

doi:10.1016/j.diabres.2013.01.031

Clinical features associated with a rapid decline in renal function among Japanese patients with type 2 diabetes mellitus: microscopic hematuria coexisting with diabetic retinopathy

Diabetes Res Clin Pract. 2013 May;100(2):e39-41. doi: 10.1016/j.diabres.2013.01.031. Epub 2013 Feb 19.

Authors

Misaki Sakata¹, Kentaro Oniki, Ayana Kita, Ayami Kajiwara, Yoshihiro Uchiyashiki, Junji Saruwatari, Akira Yoshida, Hideaki Jinnouchi, Kazuko Nakagawa

Affiliation

¹ Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.

PMID: 23433540
DOI: 10.1016/j.diabres.2013.01.031

Abstract

Four patients who exhibited the greatest decline in the estimated glomerular filtration rate [12.3-23.5 ml/min/1.73 m(2)/year] among 320 patients with type 2 diabetes and were followed for a median of 6.8 years had several clinical features in common, including marked albuminuria, microhematuria, retinopathy and poor medication adherence.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diabetes Mellitus, Type 2 / blood
Diabetes Mellitus, Type 2 / pathology*
Diabetes Mellitus, Type 2 / physiopathology*
Diabetic Retinopathy / blood
Diabetic Retinopathy / pathology
Diabetic Retinopathy / physiopathology*
Female
Glomerular Filtration Rate / physiology
Glomerulonephritis / blood
Glomerulonephritis / pathology
Glomerulonephritis / physiopathology
Hematuria / blood
Hematuria / pathology
Hematuria / physiopathology*
Humans
Male
Medication Adherence
Middle Aged