[Syphilis]

Presse Med. 2013 Apr;42(4 Pt 1):446-53. doi: 10.1016/j.lpm.2012.09.024. Epub 2013 Feb 13.
[Article in French]

Abstract

Syphilis is back since 2000. Early syphilis comprises primary syphilis, secondary syphilis and early latent syphilis (less than 1 year duration). During early phases of syphilis, patients are more contagious and neurologic complications are rare. Early neurosyphilis are mostly represented by uveitis or cranial nerves lesions. Treatment of non-neurologic syphilis are based on intramusculary injection of benzathine-penicilline G: one injection in case of early syphilis, three injections in case of late syphilis. The follow-up after treatment is based on clinical evolution and the titer of VDRL. Intravenously infusion of penicillin G is the only treatment recommended for neurosyphilis.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Cross-Cultural Comparison
  • Cross-Sectional Studies
  • Drug Administration Schedule
  • Early Diagnosis
  • Female
  • Humans
  • Incidence
  • Infant, Newborn
  • Infusions, Intravenous
  • Injections, Intramuscular
  • Male
  • Neurosyphilis / diagnosis
  • Neurosyphilis / drug therapy
  • Neurosyphilis / epidemiology
  • Neurosyphilis / transmission
  • Penicillin G / therapeutic use
  • Penicillin G Benzathine / therapeutic use
  • Population Surveillance
  • Pregnancy
  • Syphilis / diagnosis
  • Syphilis / drug therapy
  • Syphilis / epidemiology*
  • Syphilis / transmission
  • Syphilis, Cutaneous / diagnosis
  • Syphilis, Cutaneous / drug therapy
  • Syphilis, Cutaneous / epidemiology
  • Syphilis, Cutaneous / transmission
  • Syphilis, Latent / diagnosis
  • Syphilis, Latent / drug therapy
  • Syphilis, Latent / epidemiology
  • Syphilis, Latent / transmission

Substances

  • Penicillin G
  • Penicillin G Benzathine