Preparation and antimicrobial property of chitosan oligosaccharide derivative/rectorite nanocomposite

Abstract

Microwave irradiation was used to intercalate quaternized carboxymethyl chitosan oligosaccharide (QCMCO) into the layer of rectorite (REC) to prepare QCMCO/REC (QCOR) nanocomposites in 70 min, which was much faster than conventional heating method of 48 h. The structures and morphology of QCOR nanocomposites were characterized by XRD, TEM, FT-IR and zeta potential analysis, the thermal behavior and antimicrobial activity of QCOR nanocomposites were also discussed. The results revealed that the interlayer distance of QCOR nanocomposites enlarged with the increase of QCMCO content, hydrogen bonding and electrostatic interaction between QCMCO and REC took place. As compared to QCMCO, the crystallinity of QCOR nanocomposites reduced, the thermal stability of QCOR nanocomposites improved, and the inhibitory activity of QCOR nanocomposites against microorganisms was stronger, the lowest minimum inhibition concentration was only 0.025% (w/v), the antimicrobial mechanism was discussed via TEM and SEM micrographs.