Realizing the concept of a scalable artificial iris with self-regulating capability by reversible photoreaction of spiropyran dyes

Biomaterials. 2013 Apr;34(13):3159-64. doi: 10.1016/j.biomaterials.2013.01.020. Epub 2013 Feb 7.

Abstract

We report a scalable artificial iris with self-regulating spoke patterns of a liquid crystalline polymer that resemble the iris frills of the human eye. The underlying concept relies primarily on the reversible photo-induced conformation change of spiropyran dyes embedded in a transparent polymer. The spoke patterns around the scalable pupil, defined by selective wetting inscription, were produced using reactive liquid crystalline mesogens on a flexible substrate through polymerization. The self-regulation capability of our artificial iris, not requiring driving circuits and peripheral sensors, plays a central role in developing a new class of biomedical and photonic devices in a monolithic architecture.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzopyrans / chemistry
  • Benzopyrans / pharmacology*
  • Coloring Agents / chemistry
  • Coloring Agents / pharmacology*
  • Eye, Artificial*
  • Humans
  • Indoles / chemistry
  • Indoles / pharmacology*
  • Iris / drug effects*
  • Iris / radiation effects*
  • Light
  • Liquid Crystals / chemistry
  • Molecular Conformation
  • Nitro Compounds / chemistry
  • Nitro Compounds / pharmacology*
  • Photochemical Processes / drug effects*
  • Photochemical Processes / radiation effects
  • Polymers / pharmacology
  • Spectrophotometry, Ultraviolet

Substances

  • Benzopyrans
  • Coloring Agents
  • Indoles
  • Nitro Compounds
  • Polymers
  • spiropyran