Surveillance of hospital-acquired central line-associated bloodstream infections in pediatric hematology-oncology patients: lessons learned, challenges ahead

Infect Control Hosp Epidemiol. 2013 Mar;34(3):316-20. doi: 10.1086/669513. Epub 2013 Jan 22.

Abstract

Across 36 US pediatric oncology centers, 576 central line-associated bloodstream infections (CLABSIs) were reported over a 21-month period. Most infections occurred in those with leukemia and/or profound neutropenia. The contribution of viridans streptococci infections was striking. Study findings depict the contemporary epidemiology of CLABSIs in hospitalized pediatric cancer patients.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Bacteremia / epidemiology*
  • Bacteremia / microbiology
  • Catheter-Related Infections / epidemiology*
  • Catheter-Related Infections / microbiology
  • Catheterization, Central Venous / adverse effects*
  • Child
  • Child, Preschool
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Enterobacter cloacae
  • Escherichia coli
  • Female
  • Hospitalization
  • Humans
  • Infant
  • Leukemia, Myeloid, Acute / complications
  • Male
  • Neutropenia / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Prospective Studies
  • Staphylococcus
  • Time Factors
  • Viridans Streptococci
  • Young Adult