Clinical observation and nursing care on the prevention of abdominal organ cluster transplantation rejection

J Clin Nurs. 2013 Jun;22(11-12):1599-603. doi: 10.1111/jocn.12079. Epub 2013 Feb 7.

Abstract

Aims and objectives: To investigate the clinical characteristics of rejection after upper abdominal cluster transplantation.

Background: Abdominal organ cluster transplantation is used to treat multiple abdominal organ diseases. Delay in monitoring and treatment can lead to graft failure.

Design: A descriptive study.

Methods: Data collected from eight patients who underwent abdominal organ cluster transplantation from May 2004-March 2009 in our hospital were retrospectively assessed. The clinical manifestations of graft rejection and variations in characteristics associated with graft function were analysed.

Results: In all eight cases, graft function recovered successfully without rejection during the perioperative period. In one case, liver graft rejection occurred 1·5 months postoperatively, but dose adjustment of the anti-rejection drugs provided symptom relief.

Conclusions: Rejection can be prevented and cured successfully through monitoring and early detection of rejection characteristics by the nursing staff.

Relevance to clinical practice: With the increase of awareness and knowledge on the clinical observation and nursing care, the rate of transplantation rejection decreased among abdominal cluster transplant patients.

MeSH terms

  • Abdomen*
  • Adult
  • Aged
  • Female
  • Graft Rejection / nursing
  • Graft Rejection / prevention & control*
  • Humans
  • Male
  • Middle Aged
  • Organ Transplantation*