Characterization of ovarian tumors and staging ovarian cancer with 3-dimensional power Doppler angiography: correlation with pathologic findings

Int J Gynecol Cancer. 2013 Mar;23(3):469-74. doi: 10.1097/IGC.0b013e3182866679.

Abstract

Objective: The aims of this study were to evaluate ovarian tumors with 3-dimensional power Doppler angiography (3-DPDA), to determine its correlation with histology findings, and to explore its role in staging patients with ovarian cancer.

Methods: Three hundred eighteen women with an unknown unilateral pelvic mass were referred for preoperative evaluation by 3-DPDA angiography. Patients' ages ranged from 18 to 72 years (47.4 ± 13.8 years). Sonographic criteria used for the characterization of ovarian tumors were based on a system that included morphological characteristics, histological evaluation, and Power Doppler imaging.

Results: Two hundred twenty-five tumors were histopathologically diagnosed as benign and 93 as malignant. Sensitivity and specificity of the 3-DPDA of ovarian masses reached 93.5% and 92.9%, respectively, whereas positive predictive value was 84.5% and negative predictive value was 97.2%.

Conclusions: Three-dimensional power Doppler sonography is an effective imaging technique for discriminating ovarian neoplasms and classifying them according to histopathology.

MeSH terms

  • Adenocarcinoma, Clear Cell / pathology*
  • Adenocarcinoma, Mucinous / pathology*
  • Adolescent
  • Adult
  • Aged
  • Angiography
  • Carcinoma, Papillary / pathology*
  • Cystadenocarcinoma, Serous / diagnostic imaging
  • Cystadenocarcinoma, Serous / pathology*
  • Female
  • Follow-Up Studies
  • Humans
  • Imaging, Three-Dimensional
  • Middle Aged
  • Neoplasm Grading
  • Neoplasm Staging
  • Ovarian Neoplasms / pathology*
  • Prognosis
  • Sensitivity and Specificity
  • Ultrasonography, Doppler*
  • Young Adult