Flavone tetraglycosides and benzyl alcohol glycosides from the Mongolian medicinal plant Dracocephalum ruyschiana

J Nat Prod. 2013 Feb 22;76(2):186-93. doi: 10.1021/np300609u. Epub 2013 Jan 28.

Abstract

From an extract of the aerial parts of Dracocephalum ruyschiana, five new flavone tetraglycosides, five new benzyl alcohol glycosides, and 19 known compounds were isolated. The tetraglycosides contain a 7-O-β-d-glucopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)-[α-l-rhamnopyranosyl-(1→6)]-β-d-glucopyranosyl moiety. The benzyl alcohol glycosides had acyl groups on their glycosyl or aglycone moieties. The compounds were tested for antioxidant activity using DPPH. Although the new compounds were not active, phenylpropanoylquinic acid derivatives were revealed as radical scavengers in D. ruyschiana.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology
  • Benzyl Alcohol
  • Biphenyl Compounds / pharmacology
  • Flavones / chemistry
  • Flavones / isolation & purification*
  • Flavones / pharmacology
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radical Scavengers / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Lamiaceae / chemistry*
  • Molecular Structure
  • Mongolia
  • Picrates / pharmacology
  • Plants, Medicinal / chemistry*

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Flavones
  • Free Radical Scavengers
  • Glycosides
  • Picrates
  • 1,1-diphenyl-2-picrylhydrazyl
  • Benzyl Alcohol