Metastatic common bile duct cancer from pulmonary adenocarcinoma presenting as obstructive jaundice

Korean J Gastroenterol. 2013 Jan 25;61(1):50-3. doi: 10.4166/kjg.2013.61.1.50.

Abstract

We report an extremely rare case of metastatic common bile duct cancer from pulmonary adenocarcinoma presenting as obstructive jaundice. The patient was a 76-year-old male, who presented with generalized weakness and right upper quadrant pain. Plain chest X-ray noted multiple small nodules in both lung fields. Abdominal computed tomography scan showed a stricture of the mid common bile duct along with ductal wall enhancement. Endoscopic retrograde cholangiography revealed a concentric, abrupt narrowing of the mid-common bile duct suggestive of primary bile duct cancer. However, pathology comfirmed metastatic common bile duct cancer arising from pulmonary adenocarcinoma with immunohistochemical study with thyroid transcriptional factor-1 (TTF-1).

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / diagnostic imaging
  • Adenocarcinoma / pathology
  • Aged
  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / secondary
  • Bronchoscopy
  • Cholangiopancreatography, Endoscopic Retrograde
  • Common Bile Duct Neoplasms / diagnosis*
  • Common Bile Duct Neoplasms / secondary
  • DNA-Binding Proteins / metabolism
  • Humans
  • Immunohistochemistry
  • Jaundice, Obstructive / etiology*
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology
  • Male
  • Positron-Emission Tomography
  • Tomography, X-Ray Computed
  • Transcription Factors

Substances

  • DNA-Binding Proteins
  • TTF1 protein, human
  • Transcription Factors