The presence of nucleated erythrocytes and thrombocytes in reptile blood limits the use of electronic cell-counting devices for leukocytes so that manual counting techniques and evaluation of blood smears are necessary, resulting in time-consuming procedures requiring good training and experience. The evaluation of most hematologic values is complicated by the many physiologic adaptations occurring in reptiles, making references values very difficult to interpret. This article brings together most of the bibliography about hemochrome evaluation in reptiles, with schematic instruction about sample collection, handling, and evaluation. Information about evaluation of both qualitative and quantitative aspects of reptile hematology are also given.
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