The prevalence of comorbid symptoms of central sensitization syndrome among three different groups of temporomandibular disorder patients

Pain Pract. 2013 Nov;13(8):604-13. doi: 10.1111/papr.12029. Epub 2013 Jan 22.

Abstract

Aims: Symptoms of central sensitization syndrome (CSS) were evaluated among three different groups of temporomandibular disorder (TMD) patients. Additionally, TMD group differences in pain and pain-related disability were assessed, as well as emotional distress.

Methods: Participants were 250 patients with symptoms of acute TMD, recruited from dental clinics within a major metropolitan area. Sequential regressions and multivariate analyses of covariance were conducted in order to make group comparisons.

Results: Those with a TMD Muscle Disorder (ie, myofacial TMD [m-TMD]) and those with more than one TMD diagnosis had the most symptoms of CSS and higher reports of pain and pain-related disability. Moreover, emotional distress accounted for a substantial amount of the variance for physical symptoms and mediated all TMD comparisons.

Conclusions: Myofacial TMD is characterized by a high degree of comorbidity of symptoms of CSS and associated emotional distress.

Keywords: central sensitization syndrome; emotional distress; myofacial TMD; temporomandibular disorder.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Central Nervous System Sensitization*
  • Comorbidity
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Stress, Psychological / epidemiology*
  • Syndrome
  • Temporomandibular Joint Disorders / epidemiology*
  • Temporomandibular Joint Disorders / psychology*