Cutaneous adenodermatofibroma: report of 2 cases

Am J Dermatopathol. 2013 Aug;35(6):e103-5. doi: 10.1097/DAD.0b013e31827e8274.

Abstract

Dermatofibromas (DFs) are common benign fibrohistiocytic lesions, mostly affecting young adults. Many types of DF have been described, depending on architectural, cellular, and stromal peculiarities. Recently, a peculiar type of benign cutaneous tumor showing hemosiderotic DF-like stroma and apocrine glands has been described. We report 2 additional cases of DF without hemosiderotic changes showing entrapped apocrine glandular structures. We speculate about the origin of the glandular component and propose the term adenodermatofibroma for this type of lesions.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Apocrine Glands / pathology
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Dilatation, Pathologic
  • Female
  • Histiocytoma, Benign Fibrous / chemistry
  • Histiocytoma, Benign Fibrous / pathology*
  • Humans
  • Immunohistochemistry
  • Male
  • Skin Neoplasms / chemistry
  • Skin Neoplasms / pathology*
  • Stromal Cells / pathology

Substances

  • Biomarkers, Tumor