Malignant gastric lymphoma with spontaneous perforation

BMJ Case Rep. 2013 Jan 17:2013:bcr0520114251. doi: 10.1136/bcr.05.2011.4251.

Abstract

Malignant gastric lymphoma, accounting only for 1% of primary gastric carcinoma, is usually a diffuse large B-cell lymphoma. Toyota et al reported that 37% of gastric perforations involved malignancy, generally gastric carcinoma. Fukuda et al found that less than 5% of malignant gastric lymphomas perforate. While it is relatively well known that perforations often take place during chemotherapy, they are rare in patients not receiving chemotherapy. To our knowledge, spontaneous perforation is rare in gastric malignant lymphoma, having been reported in the Japanese literature only 26 times, including this case, in the last 25 years.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Endoscopy, Gastrointestinal
  • Female
  • Gastrointestinal Hemorrhage / diagnosis
  • Gastrointestinal Hemorrhage / etiology*
  • Humans
  • Lymphoma, Non-Hodgkin / complications
  • Lymphoma, Non-Hodgkin / diagnosis*
  • Lymphoma, Non-Hodgkin / therapy
  • Rupture, Spontaneous
  • Stomach Neoplasms / complications
  • Stomach Neoplasms / diagnosis*
  • Stomach Neoplasms / therapy
  • Stomach Rupture / complications*
  • Stomach Rupture / diagnosis

Supplementary concepts

  • Familial primary gastric lymphoma