Heterotopic ossification following total hip replacement for acetabular fractures

Bone Joint J. 2013 Jan;95-B(1):95-100. doi: 10.1302/0301-620X.95B1.29721.

Abstract

Early total hip replacement (THR) for acetabular fractures offers accelerated rehabilitation, but a high risk of heterotopic ossification (HO) has been reported. The purpose of this study was to evaluate the incidence of HO, its associated risk factors and functional impact. A total of 40 patients with acetabular fractures treated with a THR weres retrospectively reviewed. The incidence and severity of HO were evaluated using the modified Brooker classification, and the functional outcome assessed. The overall incidence of HO was 38% (n = 15), with nine severe grade III cases. Patients who underwent surgery early after injury had a fourfold increased chance of developing HO. The mean blood loss and operating time were more than twice that of those whose surgery was delayed (p = 0.002 and p < 0.001, respectively). In those undergoing early THR, the incidence of grade III HO was eight times higher than in those in whom THR was delayed (p = 0.01). Only three of the seven patients with severe HO showed good or excellent Harris hip scores compared with eight of nine with class 0, I or II HO (p = 0.049). Associated musculoskeletal injuries, high-energy trauma and head injuries were associated with the development of grade III HO.The incidence of HO was significantly higher in patients with a displaced acetabular fracture undergoing THR early compared with those undergoing THR later and this had an adverse effect on the functional outcome.

Publication types

  • Evaluation Study

MeSH terms

  • Acetabulum / injuries*
  • Adult
  • Aged
  • Aged, 80 and over
  • Arthroplasty, Replacement, Hip*
  • Follow-Up Studies
  • Fractures, Bone / surgery*
  • Humans
  • Incidence
  • Middle Aged
  • Ossification, Heterotopic / diagnostic imaging
  • Ossification, Heterotopic / epidemiology
  • Ossification, Heterotopic / etiology*
  • Postoperative Complications* / diagnostic imaging
  • Postoperative Complications* / epidemiology
  • Radiography
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome