Neurocognitive development of children born small for gestational age (SGA). An update

Pediatr Endocrinol Rev. 2012 Aug;9(4):716-26.

Abstract

The aim of the present study is to confirm that being born SGA is a serious risk for a negative neurocognitive development. 233 cases have been controlled yearly and longitudinally by the same investigator, some of them 11 times, showing 25,8 % an IQ less than 2 SD, being less affected the catch-up + group (15 %), compared to the catch-up - group (31,4 %). The GH therapy (n 64) started before the age of 6 (n 38) or after 6 (n 26), doesn't improve the negative outcome.

MeSH terms

  • Adolescent
  • Brain / growth & development*
  • Child
  • Child, Preschool
  • Cognition / physiology
  • Female
  • Follow-Up Studies
  • Growth Disorders / drug therapy*
  • Growth Disorders / epidemiology
  • Human Growth Hormone / therapeutic use*
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Small for Gestational Age / growth & development*
  • Longitudinal Studies
  • Male
  • Risk Factors

Substances

  • Human Growth Hormone