Mental disorders in patients with metabolic syndrome. The key role of central obesity

Eat Weight Disord. 2012 Dec;17(4):e259-66. doi: 10.3275/8809. Epub 2013 Jan 8.

Abstract

Background: The Authors sought to evaluate current prevalence of mental disorders in patients affected by metabolic syndrome compared with patients affected by central obesity alone.

Methods: 186 (63.5%) patients affected by central obesity and 107 (36.5%) affected by metabolic syndrome according to ICF criteria were interviewed by means of SCID I.

Results: Axis I current prevalence was respectively 45.7% and 44.9% among patients with central obesity and patients with metabolic syndrome, differences which were not significant. No statistically significant differences were found between groups as far as each single axis I diagnostic category was concerned. Moreover, current prevalence of any axis I, anxiety and mood disorders were independent of the number of components of metabolic syndrome.

Conclusion: metabolic syndrome is associated to an higher risk for current mental disorders, which seems to be mainly due to the strong association of central obesity to psychopathology.

MeSH terms

  • Adult
  • Analysis of Variance
  • Anxiety Disorders / epidemiology*
  • Cohort Studies
  • Humans
  • Male
  • Metabolic Syndrome / physiopathology
  • Metabolic Syndrome / psychology*
  • Middle Aged
  • Mood Disorders / epidemiology*
  • Obesity, Abdominal / physiopathology
  • Obesity, Abdominal / psychology*
  • Prevalence
  • Psychiatric Status Rating Scales
  • Psychopathology*
  • Risk Factors