Mixed infection caused by Lecythophora canina sp. nov. and Plectosphaerella cucumerina in a German shepherd dog

Med Mycol. 2013 Jul;51(5):455-60. doi: 10.3109/13693786.2012.754998. Epub 2013 Jan 7.

Abstract

We describe an opportunistic, disseminated infection in a German shepherd dog associated with two fungal organisms not previously reported to cause disease. Lecythophora canina, a new species here described, was isolated from an osteolytic bone lesion. A fine needle aspirate of the lesion demonstrated septate hyphae. Plectospharella cucumerina (anamorph Plectosporium tabacinum) was isolated from a urine sample. Clinical manifestations were blindness, altered mentation, and osteomyelitis. Treatment with itraconazole and terbinafine for greater than one year resulted in stable clinical disease.

MeSH terms

  • Animals
  • Ascomycota / classification*
  • Ascomycota / genetics
  • Ascomycota / isolation & purification*
  • Biopsy, Fine-Needle
  • Bone and Bones / diagnostic imaging
  • Coinfection / microbiology
  • Coinfection / veterinary*
  • DNA, Fungal / chemistry
  • DNA, Fungal / genetics
  • DNA, Ribosomal Spacer / chemistry
  • DNA, Ribosomal Spacer / genetics
  • Dog Diseases / microbiology*
  • Dogs
  • Microscopy
  • Molecular Sequence Data
  • Mycoses / microbiology
  • Mycoses / veterinary*
  • Opportunistic Infections / microbiology
  • Opportunistic Infections / veterinary
  • Osteomyelitis / microbiology
  • Osteomyelitis / veterinary
  • Radiography
  • Sequence Analysis, DNA
  • Urine / microbiology

Substances

  • DNA, Fungal
  • DNA, Ribosomal Spacer

Associated data

  • GENBANK/HE974355
  • GENBANK/HE974356
  • GENBANK/JX431887
  • GENBANK/JX431888
  • GENBANK/JX481774
  • GENBANK/JX481775