No abstract available
MeSH terms
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Analgesics, Opioid / blood
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Analgesics, Opioid / pharmacokinetics*
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Analgesics, Opioid / therapeutic use
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Aryl Hydrocarbon Hydroxylases / genetics*
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Aryl Hydrocarbon Hydroxylases / metabolism
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Biotransformation
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Cytochrome P-450 CYP2B6
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Gene Frequency
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Genotype
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Heroin Dependence / blood
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Heroin Dependence / rehabilitation*
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Humans
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Linear Models
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Linkage Disequilibrium
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Liver / enzymology*
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Methadone / blood
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Methadone / pharmacokinetics*
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Methadone / therapeutic use
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Opiate Substitution Treatment*
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Oxidoreductases, N-Demethylating / genetics*
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Oxidoreductases, N-Demethylating / metabolism
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Pharmacogenetics
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Phenotype
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Polymorphism, Single Nucleotide*
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Pregnane X Receptor
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Receptors, Steroid / genetics*
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Receptors, Steroid / metabolism
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Taiwan
Substances
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Analgesics, Opioid
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Pregnane X Receptor
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Receptors, Steroid
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Aryl Hydrocarbon Hydroxylases
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CYP2B6 protein, human
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Cytochrome P-450 CYP2B6
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Oxidoreductases, N-Demethylating
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Methadone
Associated data
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ClinicalTrials.gov/NCT01059747