Mutation analysis of microRNA-7 gene in Chinese patients with Parkinson's disease

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 Dec;37(12):1189-92. doi: 10.3969/j.issn.1672-7347.2012.12.001.

Abstract

Objective: To investigate the mutation of small sequence changes in microRNA-7 gene in Chinese patients with Parkinson's disease (PD).

Methods: We analyzed miR-7 variants in 225 PD patients from Chinese Han group by DNA sequence.

Results: None of the patients had miR-7 variants.

Conclusion: MiR-7 variation is not associated with PD in Chinese patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Base Sequence
  • China / ethnology
  • Female
  • Humans
  • Male
  • MicroRNAs / genetics*
  • Middle Aged
  • Molecular Sequence Data
  • Mutation*
  • Parkinson Disease / genetics*

Substances

  • MIRN7 microRNA, human
  • MicroRNAs