Current genomic editing approaches in avian transgenesis

Tae Sub Park; Kyung Soo Kang; Jae Yong Han

doi:10.1016/j.ygcen.2012.11.020

Current genomic editing approaches in avian transgenesis

Gen Comp Endocrinol. 2013 Sep 1:190:144-8. doi: 10.1016/j.ygcen.2012.11.020. Epub 2012 Dec 14.

Authors

Tae Sub Park¹, Kyung Soo Kang, Jae Yong Han

Affiliation

¹ WCU Biomodulation Major, Department of Agricultural Biotechnology, Research Institute for Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.

PMID: 23247275
DOI: 10.1016/j.ygcen.2012.11.020

Abstract

The chicken was domesticated from Red Jungle Fowl over 8000years ago and became one of the major food sources worldwide. At present, the poultry industry is one of the largest industrial animal stocks in the world, and its economic scale is expanding significantly with increasing consumption. Additionally, since Aristotle used chicken eggs as a model to provide remarkable insights into how life begins, chickens have been used as invaluable and powerful experimental materials for studying embryo development, immune systems, biomedical processes, and hormonal regulation. Combined with advancements in efficient transgenic technology, avian models have become even more important than would have been expected.

Keywords: Genomic editing; Model animal; Primordial germ cell; Transgenesis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Animals, Genetically Modified
Birds / genetics*
Birds / physiology
Chickens
Gene Transfer Techniques*
Genomics / methods*