A young newlywed man experienced severe dyspnea and physiological compromise after his first and second experiences with sexual intercourse. The physiological and psychological stresses put his marriage at risk. All resolved after diagnosis and treatment. This is a case of a rare but known entity-asthma provoked by sexual activity at a level of physiological stress below that required to trigger exercise-induced asthma. The scant literature on this entity was reviewed for which the term "honeymoon asthma" is suggested and is literally true in this case.