Lost in presumption: stochastic reactions in spatial models

Nat Methods. 2012 Dec;9(12):1163-6. doi: 10.1038/nmeth.2253.

Abstract

Physical modeling is increasingly important for generating insights into intracellular processes. We describe situations in which combined spatial and stochastic aspects of chemical reactions are needed to capture the relevant dynamics of biochemical systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Cell Physiological Phenomena*
  • Computer Simulation
  • Diffusion
  • Models, Biological*
  • Molecular Dynamics Simulation*
  • Stochastic Processes*