High specific activity ⁶¹Cu via ⁶⁴Zn(p,α)⁶¹Cu reaction at low proton energies

Stefan Thieme; Martin Walther; Stephan Preusche; Johan Rajander; Hans-Jürgen Pietzsch; Jan-Olof Lill; Michael Kaden; Olof Solin; Jörg Steinbach

doi:10.1016/j.apradiso.2012.11.007

High specific activity ⁶¹Cu via ⁶⁴Zn(p,α)⁶¹Cu reaction at low proton energies

Appl Radiat Isot. 2013 Feb:72:169-76. doi: 10.1016/j.apradiso.2012.11.007. Epub 2012 Nov 19.

Authors

Stefan Thieme¹, Martin Walther, Stephan Preusche, Johan Rajander, Hans-Jürgen Pietzsch, Jan-Olof Lill, Michael Kaden, Olof Solin, Jörg Steinbach

Affiliation

¹ Institute of Radiopharmacy, Helmholtz-Zentrum Dresden-Rossendorf, P.O. Box 510 119, 01314 Dresden, Germany.

PMID: 23220029
DOI: 10.1016/j.apradiso.2012.11.007

Abstract

The PET radionuclide (61)Cu is accessible through several nuclear reactions. Besides the common production route via (61)Ni(p,n)(61)Cu the (64)Zn(p,α)(61)Cu reaction offers some advantages. Especially the comparatively cheap enriched (64)Zn makes this process economical. For fast product purification and recycling of target material an ion exchange cascade was developed. In addition a separation technique with a copper selective resin was tested. (61)Cu with specific activities up to 1000 GBq/μmol was produced with these methods.