Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins

J Bacteriol. 2012 Dec;194(24):7010-1. doi: 10.1128/JB.01880-12.

Abstract

Mycobacterium hassiacum is a rapidly growing mycobacterium isolated from human urine and so far the most thermophilic among mycobacterial species. Its thermotolerance and phylogenetic relationship to M. tuberculosis render its proteins attractive tools for crystallization and structure-guided drug design. We report the draft genome sequence of M. hassiacum DSM 44199.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins* / metabolism
  • Base Composition
  • Base Sequence
  • DNA, Bacterial / genetics
  • Genome, Bacterial*
  • Hot Temperature
  • Humans
  • Molecular Sequence Data
  • Nontuberculous Mycobacteria / classification
  • Nontuberculous Mycobacteria / genetics*
  • Nontuberculous Mycobacteria / isolation & purification
  • Phylogeny
  • Protein Stability
  • RNA, Bacterial / genetics
  • Sequence Analysis, DNA
  • Urine / microbiology

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • RNA, Bacterial