Genome sequences of two multidrug-resistant Acinetobacter baumannii strains isolated from a patient before and after treatment with tigecycline

Xiaoting Hua; Hua Zhou; Yan Jiang; Ye Feng; Qiong Chen; Zhi Ruan; Yunsong Yu

doi:10.1128/JB.01887-12

Genome sequences of two multidrug-resistant Acinetobacter baumannii strains isolated from a patient before and after treatment with tigecycline

J Bacteriol. 2012 Dec;194(24):6979-80. doi: 10.1128/JB.01887-12.

Authors

Xiaoting Hua¹, Hua Zhou, Yan Jiang, Ye Feng, Qiong Chen, Zhi Ruan, Yunsong Yu

Affiliation

¹ Department of Infectious Diseases, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.

Abstract

Acinetobacter baumannii is a Gram-negative bacterium which emerged as a significant nosocomial pathogen worldwide. To investigate the molecular basis of the tigecycline-resistant mechanism, we determined the genome sequences of two multidrug-resistant A. baumannii strains isolated from a patient before and after treatment with tigecycline.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acinetobacter Infections / drug therapy
Acinetobacter Infections / microbiology*
Acinetobacter baumannii / drug effects
Acinetobacter baumannii / genetics*
Acinetobacter baumannii / isolation & purification
Anti-Bacterial Agents / therapeutic use*
Cross Infection / drug therapy
Cross Infection / microbiology
DNA, Bacterial / genetics
Drug Resistance, Multiple, Bacterial / genetics
Genome, Bacterial*
Humans
Interspersed Repetitive Sequences
Minocycline / analogs & derivatives*
Minocycline / therapeutic use
Molecular Sequence Data
Sequence Analysis, DNA
Tigecycline

Substances

Anti-Bacterial Agents
DNA, Bacterial
Tigecycline
Minocycline

Associated data

GENBANK/AMGR00000000
GENBANK/AMGR01000000
GENBANK/AMGS00000000
GENBANK/AMGS01000000