[Qianlieping capsule plus alpha-blocker for chronic non-bacterial prostatitis: analysis of 220 cases]

Zhonghua Nan Ke Xue. 2012 Sep;18(9):856-8.
[Article in Chinese]

Abstract

Objective: To investigate the clinical effects of Qianlieping Capsule combined with alpha-receptor blocker tamsulosin on chronic non-bacterial prostatitis (CNBP).

Methods: We assigned 220 CNBP patients to three groups to receive oral Qianlieping Capsule (2.0 g tid) plus alpha-receptor blocker tamsulosin (0.2 mg qd) (n = 98), Qianlieping Capsule alone at 2.0 g tid (n = 66), and tamsulosin alone at 0.2 mg qd (n = 56) , respectively. After 6 weeks of medication, we assessed the therapeutic effects according to the NIH-CPSI scores and the number of small particles of lecithin (SPL) in the prostatic fluid after treatment.

Results: Qianlieping Capsule alone increased the number of SPL by 46.9% and reduced the NIH-CPSI score by 24.4%. Combination of Qianlieping and tamsulosin more significantly increased the number of SPL (61.4%) and decreased the NIH-CPSI score (42.3%) than tamsulosin alone (33.7% and 28.6%) (P < 0.01).

Conclusion: Qianlieping Capsule chronic is effective for chronic non-bacterial prostatitis, and the combination of Qianlieping Capsule with tamsulosin produces even better effect than tamsulosin alone.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adrenergic alpha-Antagonists / administration & dosage
  • Adrenergic alpha-Antagonists / therapeutic use*
  • Adult
  • Capsules
  • Chronic Disease
  • Drugs, Chinese Herbal / administration & dosage
  • Drugs, Chinese Herbal / therapeutic use*
  • Humans
  • Male
  • Phytotherapy*
  • Prostatitis / drug therapy*
  • Sulfonamides / administration & dosage
  • Sulfonamides / therapeutic use
  • Tamsulosin
  • Treatment Outcome
  • Young Adult

Substances

  • Adrenergic alpha-Antagonists
  • Capsules
  • Drugs, Chinese Herbal
  • Sulfonamides
  • Tamsulosin